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MassWorks
CLIPS / sCLIPS


MassWorks

Introduction

MassWorks ´Â ´ÜÀ§Áú·® ÇØ»óµµ(unit mass resolution)ÀÇ single ¶Ç´Â triple quadrupoles ¹æ½ÄÀÇ GC/MS³ª
LC/MS·Î formula ID¸¦ ÇÒ ¼ö ÀÖ´Â CLIPS ¹öÀü°ú °íÇØ»óµµ(high resolution) Áú·®ºÐ¼®±âÀÇ formula ID ±â´ÉÀ»
Çâ»ó½ÃÅ°´Â sCLIPS ¹öÀüÀÌ ÀÖ½À´Ï´Ù .

Learn About CLIPS
Learn About sCLIPS
 

MassWorks´Â Cerno »çÀÇ Æ¯ÇãÀÎ MSIntegrity¢â ±â¼úÀ» È°¿ëÇÏ¿© ´ÜÀ§Áú·® ÇØ»óµµÀÇ º¸ÆíÀûÀÎ Áú·®ºÐ¼®±â
¿¡¼­ ³ôÀº Áú·® Á¤È®µµ(high mass accuracy)¿Í ³ôÀº ½ºÆåÆ®·³ Á¤È®µµ(high spectra accuracy)¸¦ ¾òÀ» ¼ö
ÀÖ´Â »ç¿ëÀÌ Æí¸®ÇÑ post acquisition ¼ÒÇÁÆ®¿þ¾î ÆÐÅ°ÁöÀÔ´Ï´Ù. ¶ÇÇÑ MassWorks sCLIPS ´Â Ç¥Áع°ÁúÀ»
»ç¿ëÇÏÁö ¾Ê°íµµ Á¤È®ÇÑ ¼±Çüº¸Á¤(line-shape calibration)À¸·Î ³ôÀº ½ºÆåÆ®·³ Á¤È®µµ¸¦ Á¦°øÇÕ´Ï´Ù. MassWorks´Â ½Å¼ÓÇÏ°í ´ÙÀç ´Ù´ÉÇÑ Áú·®ºÐ¼® ÀÀ¿ëÇÁ·Î±×·¥ ÆÐÅ°Áö·Î ´ÜÀ§Áú·®ÇØ»óµµ ½Ã½ºÅÛ¿¡¼­ ÃÖ´ë
100¹èÀÇ Áú·®Á¤È®µµ Çâ»ó°ú, °í/ÀúÇØ»óµµ ½Ã½ºÅÛ¿¡¼­ ÃÖ´ë 99.9% ½ºÆåÆ®·³ Á¤È®µµ¸¦ ¾òÀ» ¼ö ÀÖ´Â °­·ÂÇÑ MSIntegrity º¸Á¤±â¼úÀÌ ÅëÇյǾú½À´Ï´Ù. ³í¸®ÀûÀÎ ¼öÇÐÀû ¿ø¸®¿Í »õ·Î¿î º¸Á¤±â¼úÀÇ °áÇÕÀ¸·Î, Cerno
¹æ¹ý·ÐÀº °í/ÀúÇØ»óµµÀÇ ¸ðµç Áú·®ºÐ¼® µ¥ÀÌÅÍ¿¡ ÀÇ¹Ì ÀÖ´Â °³¼±À» Á¦°øÇÒ ¼ö ÀÖ½À´Ï´Ù.

 
 
¡¤ Quadrupole GC/MS ¶Ç´Â LC/MS ¿¡¼­ ³ôÀº Áú·®Á¤È®µµ (ÃÖ´ë 5ppm ¼öÁرîÁö)
¡¤ ¸ðµç ½Ã½ºÅÛ¿¡¼­ Çâ»óµÈ ½ºÆåÆ®·³ Á¤È®µµ (Spectral Accuracy) (ÃÖ´ë 99.9 % ±îÁö)
¡¤ È¿°úÀûÀÎ ³ëÀÌÁî ÇÊÅ͸µ (ÃÖ´ë 3 ¹è)
¡¤ Cerno Calibration Tutorial
¡¤ New V2.0! MassWorks Brochure (English PDF)
¡¤ Press Release (PDF)
 
 

"The ability to provide the elemental identification of unknown compounds on a routine basis by  any scientist is now within one's reach." Read all quotes

Eli Lily Poster from ASMS 2007

 
 
 

 

MassWorks
CLIPS / sCLIPS

 

CLIPS

Single ¶Ç´Â triple quad GC/MS ³ª LC/MS ±â±âÀÇ Æ÷¹Ä¶ó µ¿Á¤(Formula ID) ÀÌÂ÷¿øÀûÀÎ formula ID ¸¦
Á¦°øÇÕ´Ï´Ù
 
 
¡¤ Áú·®Á¤È®µµ 5ppm
¡¤ ½ºÆåÆ®·³ Á¤È®µµ (Spectral Accuracy) 99.9%
¡¤ Cerno Calibration Tutorial
¡¤ Learn more about CLIPS (PDF)
¡¤ Technical - Learn about line-shape calibration
 
 
" The program is very easy to learn, it literally took minutes to get the first exciting results.
 On our 10 year-old triple quad, we manage to achieve mass accuracies of 10ppm or better
 routinely.  It has become an integral part of our characterization pipeline for newly
synthesized compounds.
"
 Read all quotes


Dr. Alexander Leitner
University of Vienna
 
 
 

 

sCLIPS

±â±âÀÇ ¼±Çü º¸Á¤°ú ÀÌ·Ð ÃøÁ¤°ª ´ëºñ Áú·®ºÐ¼® °ªÀÇ ºñ±³·Î ¹ÌÁö À̿¿¡ ´ëÇÑ Èĺ¸ Æ÷¹Ä¶ó
(candidate formula)ÀÇ Á¤È®ÇÑ µ¿À§¿ø¼Ò ¸ðµ¨¸µ(isotope modeling)À» ÇÒ ¼ö ÀÖ½À´Ï´Ù.
 
 
¡¤ TOF, OrbiTrap, FT-ICR, ±×¸®°í °íÇØ»óµµ quadrupole MS ¿¡ »ç¿ë
¡¤ Ç¥Áع°Áú ¾øÀ̵µ Á¤È®ÇÑ ¼±Çü º¸Á¤
¡¤ ÃøÁ¤ ½ºÆåÆ®·³°ú ÀÌ·Ð ½ºÆåÆ®·³ °£ÀÇ 99.9% ±îÁö ºñ±³ Spectral Accuracy
¡¤ Cerno Calibration Tutorial
¡¤ NEW! Learn more about sCLIPS (PDF)
¡¤ sCLIPS poster from ASMS 2008 (PDF)
¡¤ Technical - sCLIPS Article from Spectroscopy Mag
 
 

"The use of exact isotope modeling [with MassWorks] is key to unique formula ID [with FT-ICR]  and profile mode peakshape calibration is needed to achieve the required Spectral Accuracy.
" Read all quotes

Boehringer Ingelheim Pharmaceuticals Poster from ASMS 2008