13C Stable Isotope Labeled Glycan Standards

CarboQuant standards는 질량분석기를 이용한 glycan 절대 정량용 internal standard로 사용하기 위한 합성 C13 labeled N-glycan입니다. Single standards 또는 정량 소프트웨어와 함께 glycan 분석에 필요한 모든 시약 및 소모품을 포함한 키트 형태로 제공됩니다. 완벽하게 합성하여 MS와 NMR로 특성분석한 모든 N-acetylglucosamine은 최대 10 Da 질량 차이로 13C stable isotope로 labeled 되어 peak가 중복되지 않습니다.

CarboQuant standards

• >95% 순도
• MS와 NMR로 특성분석
• 최대 10 Da mass gain. No peak overlap
• 모든 N-acetylglucosamine에 13C stable isotope표지
• Quantified internal standards (qNMR )
• Broad coverage of N-glycan structures

Applications

• Internal glycan standards를 사용한 glycan 분석 workflow 개선
• Internal glycan standards를 사용한 분석법의 견고성 향상
• Biofluids에 포함된 개별 glycans의 정량화
• MALDI-TOF MS를 이용한 매우 빠른 샘플 준비 및 데이터 수집을 통해 바이오마커 연구 및 바이오의약품 연구에서 정량적 glycan profiles 생성

Glycan Standard ¹³C Paucimannose Man3

• 2 x ¹³C per GlcNAc
• +4 Da mass gain
• Molecular Formula : C₃₀¹³C₄H₅₈N₂O₂₆
• Monoisotopic mass : 914.34098

Glycan Standard ¹³C Paucimannose Man5

• 2 x ¹³C per GlcNAc
• +4 Da mass gain
• Molecular Formula : C₄₂¹³C₄H₇₈N₂O₃₆
• Monoisotopic mass : 1238.44663

Glycan Standard ¹³C truncated MGn(6)

• 2 x ¹³C per GlcNAc
• +6 Da mass gain
• Molecular Formula : C₃₆¹³C₆H₇₁N₃O₃₁
• Monoisotopic mass : 1119.42084

Glycan Standard ¹³C truncated MGn(3)

• 2 x ¹³C per GlcNAc
• +6 Da mass gain
• Molecular Formula : C₄₂¹³C₆H₈₁N₃O₃₅
• Monoisotopic mass : 1265.48519

Glycan Standard ¹³C Biantennary G0

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₄₂¹³C₈H₈₄N₄O₃₆
• Monoisotopic mass : 1324.51337

Glycan Standard ¹³C Biantennary G0F

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₄₈¹³C₈H₉₄N₄O₄₀
• Monoisotopic mass : 1470.57127

Glycan Standard ¹³C Biantennary G1(3)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₄₈¹³C₈H₉₄N₄O₄₁
• Monoisotopic mass : 1486.56619

Glycan Standard ¹³C Biantennary G1(6)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₄₈¹³C₈H₉₄N₄O₄₁
• Monoisotopic mass : 1486.56619

Glycan Standard ¹³C Biantennary G1(6)F

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₅₄¹³C₈H₁₀₄N₄O₄₅
• Monoisotopic mass : 1486.56619

Glycan Standard ¹³C Biantennary G2

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₅₄¹³C₈H₁₀₄N₄O₄₆
• Monoisotopic mass : 1648.61901

Glycan Standard ¹³C Biantennary G2F

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₆₀¹³C₈H₁₁₄N₄O₅₀
• Monoisotopic mass : 1796.91848

Glycan Standard ¹³C Biantennary A1(3)(Sial α-2,3)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₆₅¹³C₈H₁₂₁N₅O₅₄
• Monoisotopic mass : 1777.6616

Glycan Standard ¹³C Biantennary A1(6)F(Sial α-2,3)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₆₅¹³C₈H₁₂₁N₅O₅₃
• Monoisotopic mass : 1923.71951

Glycan Standard ¹³C Biantennary G2A1(3)(Sial α-2,3)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₆₅¹³C₈H₁₂₁N₅O₅₄
• Monoisotopic mass : 1936.71443

Glycan Standard ¹³C Biantennary G2A1(6)F(Sial α-2,3)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₇₁¹³C₈H₁₃₁N₅O₅₈
• Monoisotopic mass : 2085.77234

Glycan Standard ¹³C Biantennary A2 2x(Sial α-2,3)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₇₆¹³C₈H₁₃₈N₆O₆₂
• Monoisotopic mass : 2230.80984

Glycan Standard ¹³C Biantennary A2F 2x(Sial α-2,3)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₈₂¹³C₈H₁₄₈N₆O₆₆
• Monoisotopic mass : 2376.86775

Glycan Standard ¹³C Biantennary G2A1(3)(Sial α-2,6)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₆₅¹³C₈H₁₂₁N₅O₅₄
• Monoisotopic mass : 1936.71443

Glycan Standard ¹³C Biantennary G2A1(6)F(Sial α-2,6)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₇₁¹³C₈H₁₃₁N₅O₅₈
• Monoisotopic mass : 2085.77234

Glycan Standard ¹³C Biantennary A2 2x(Sial α-2,6)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₇₆¹³C₈H₁₃₈N₆O₆₂
• Monoisotopic mass : 2230.80984

Glycan Standard ¹³C Biantennary A2F 2x(Sial α-2,6)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₈₂¹³C₈H₁₄₈N₆O₆₆
• Monoisotopic mass : 2376.86775

Glycan Standard ¹³C Biantennary bG0

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₄₈¹³C₁₀H₉₇N₅O₄₁
• Monoisotopic mass : 1529.59945

Glycan Standard ¹³C Biantennary bG1(6)

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₅₄¹³C₁₀H₁₀₇N₅O₄₆
• Monoisotopic mass : 1691.65227

Glycan Standard ¹³C Biantennary bG2

• 2 x ¹³C per GlcNAc
• +8 Da mass gain
• Molecular Formula : C₆₀¹³C₁₀H₁₁₇N₅O₅₁
• Monoisotopic mass : 1853.70509

Glycan Standard ¹³C Biantennary bA2 2x(Sial α-2,6)

• 2 x ¹³C per GlcNAc
• +10 Da mass gain
• Molecular Formula : C₈₂¹³C₁₀H₁₅₁N₇O₆₇
• Monoisotopic mass : 2435.89593

Glycan Standard ¹³C Biantennary bA2F 2x(Sial α-2,6)

• 2 x ¹³C per GlcNAc
• +10 Da mass gain
• Molecular Formula : C₈₈¹³C₁₀H₁₆₁N₇O₇₁
• Monoisotopic mass : 2581.95384

Glycan Standard ¹³C Triantennary A3G0

• 2 x ¹³C per GlcNAc
• +10 Da mass gain
• Molecular Formula : C₄₈¹³C₁₀H₉₇N₅O₄₁
• Monoisotopic mass : 1529.59945

Glycan Standard ¹³C Triantennary A3G0F

• 2 x ¹³C per GlcNAc
• +10 Da mass gain
• Molecular Formula : C₅₄¹³C₁₀H₁₀₇N₅O₄₅
• Monoisotopic mass : 1675.65736

Glycan Standard ¹³C Triantennary A3G3F

• 2 x ¹³C per GlcNAc
• +10 Da mass gain
• Molecular Formula : C₇₂¹³C₁₀H₁₃₇N₅O₆₀
• Monoisotopic mass : 2161.81583

Glycan Standard ¹³C Tetraantennary A4-G3bcd

• 1 x ¹³C per GlcNAc
• +6 Da mass gain
• Molecular Formula : C₇₈¹³C₆H₁₄₀N₆O₆₁
• Monoisotopic mass : 2214.82387

Glycan Standard ¹³C Tetraantennary A4-LacNAc-G4

• 1 x ¹³C per GlcNAc
• +7 Da mass gain
• Molecular Formula : C₉₇¹³C₇H₁₇₃N₇O₇₆
• Monoisotopic mass : 2743.01224

Glycan Standard ¹³C Tetraantennary A4-G4

• 1 x ¹³C per GlcNAc
• +6 Da mass gain
• Molecular Formula : C₈₄¹³C₆H₁₅₀N₆O₆₆
• Monoisotopic mass : 2376.87669

Glycan Standard ¹³C Tetraantennary A4-G3abd

• 1 x ¹³C per GlcNAc
• +6 Da mass gain
• Molecular Formula : C₇₈¹³C₆H₁₄₀N₆O₆₁
• Monoisotopic mass : 2214.8236